Estrovera 30 Tablets

SKU ET30

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Estrovera 30 Tablets

SKU ET30

Plant-derived alternative for Menopause relief & Perimenopause support.

Highlights

  • Try this best seller on our Money Back Guarantee*
  • Formulated with clinically proven proprietary extract ERr 731®.
  • Relieves hot flushes & irritability.
  • Reduces restless sleep & fatigue.
  • Supports healthy libido.
  • Decreases vaginal dryness.
  • Reduces muscle aches & mild joint pain.
Read more

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Always read the label and follow the directions for use. Read the warnings before purchase.

Hot Flush Relief from 4 weeks

Clinically Proven Ingredient

One Daily Dose

Vegan

Description

Metagenics Estrovera® is a revolutionary option for women seeking a solution to the challenges of menopause. With just one mini tablet per day, you can find relief from 8 common menopause symptoms and support through perimenopause, helping you feel like yourself again.

Formulated with a clinically proven proprietary extract, known as ERr 731®, a plant-derived alternative for menopause.

Track your menopause symptoms, monitor progress and identify trends with our Menopause Guide.

Benefits of Estrovera®.

Up to 80% reduction in menopausal symptoms*:

  • Relieves hot flushes from 4 weeks^
  • Relieves irritability fatigue
  • Reduce disturbed and restless sleep
  • Decreases vaginal dryness
  • Supports healthy libido
  • Reduces muscle aches mild joint pain

How does Estrovera® help with Perimenopause?

Estrovera® helps perimenopausal women maintain general health and wellbeing, ensuring they feel their best during this transitional phase, as well as:

  • Supports emotional wellbeing
  • Soothe & calms nerves
  • Maintains healthy libido sexual function

Recommended Use:

For optimal results, we recommend taking Estrovera® for at least 90 days. 

Take control of your menopause journey with Estrovera®. Feel confident, supported, and ready to embrace this new chapter of your life. 

*Hasper et al. Long-term efficacy and safety of the special extract ERr 731® Rheum rhaponticum. 2009. 
^Survey conducted online by Metagenics September 2020 with 75 women currently taking Estrovera.

Directions

Adult Women only: Take 1 mini tablet daily with food, or as directed by your healthcare professional.

Warnings

This product contains Rheum rhaponticum and this product may have laxative effect.

If symptoms persist consult your healthcare professional.
Do not use if cap and/or seals are missing or broken.

Storage

Store below 30°C.

Key Ingredients

ERr 731®

Active Ingredients

Each tablet contains

Rheum rhaponticum, dry root extract

4 mg

From dry root (ERr 731®)

84 mg

Free from:

  • Animal Products
  • Corn
  • Dairy Protein
  • Lactose
  • Eggs
  • Gluten
  • Wheat
  • Nuts
  • Yeast
  • Soy Protein
  • Artificial Colours
  • Artificial Flavours
  • Artificial Preservatives
  • Starches

Excipients:

  • croscarmellose sodium, ethylcellulose, hyprolose, hypromellose, medium chain triglycerides, microcrystalline cellulose, oleic acid, purified water, silicon dioxide, sodium alginate, stearic acid, strong ammonia solution

Delivery

Metro Areas

  • Express Shipping (1-3 days) – Free over $80, otherwise $13.95

Non-Metro Areas

  • Express Shipping (2-5 days) – Free over $80, otherwise $13.95

Remote Areas

  • Express Shipping (3-14 days) – $13.95

Free Shipping for orders over $80 (excludes remote/offshore areas and certain conditions). Read full shipping policy.

Metagenics Estrovera bottle for menopause relief, highlighting benefits such as managing 8 symptoms with one daily capsule, providing relief from hot flushes, and being practitioner-formulated with clinically proven ingredients.
Metagenics Estrovera bottle for menopause relief, highlighting benefits such as managing 8 symptoms with one daily capsule, providing relief from hot flushes, and being practitioner-formulated with clinically proven ingredients.
Metagenics Estrovera menopause support featuring ERr 731®, a plant-derived and clinically proven ingredient designed to relieve 8 common menopause symptoms, with visual of the supplement tablet.
Metagenics Estrovera menopause support featuring ERr 731®, a plant-derived and clinically proven ingredient designed to relieve 8 common menopause symptoms, with visual of the supplement tablet.
Siberian rhubarb flowers representing ERr 731®, a clinically proven ingredient that mimics oestrogen receptor beta to relieve perimenopausal symptoms naturally, with noticeable effects in just 4 weeks.
Siberian rhubarb flowers representing ERr 731®, a clinically proven ingredient that mimics oestrogen receptor beta to relieve perimenopausal symptoms naturally, with noticeable effects in just 4 weeks.
Infographic illustrating the three stages of menopause—Perimenopause, Menopause, and Postmenopause—highlighting hormonal changes, symptom progression, and menstrual cycle patterns across an 8 to 10 year transition period.
Infographic illustrating the three stages of menopause—Perimenopause, Menopause, and Postmenopause—highlighting hormonal changes, symptom progression, and menstrual cycle patterns across an 8 to 10 year transition period.

Frequently asked questions

How long does it take to see results from using Estrovera®?

Within 4 weeks, ERr 731™ can improve 11 perimenopause symptoms by 14% to 28%, including, poor sleep, irritability, fatigue, sore joints and vaginal dryness.1 After 12 weeks of ERr 731™ use, perimenopausal symptoms were shown to improve by 45% to 78%.1,2

References
[1] Shah J, Chandanani S, Reddy J, et al. Evaluation of the efficacy and safety of Rheum rhaponticum Root extract (ERr 731) for menopausal symptoms in perimenopausal Indian women: an interim analysis. J Mid-life Heal. 2021;12(2):108-115. doi:10.4103/jmh.jmh_86_21

[2] Hasper I, Ventskovskiy BM, Rettenberger R, Heger PW, Riley DS, Kaszkin-Bettag M. Long-term efficacy and safety of the special extract ERr 731 of Rheum rhaponticum in perimenopausal women with menopausal symptoms. Menopause. 2009 Jan-Feb;16(1):117-31. doi: 10.1097/GME.0b013e3181806446

Is Estrovera® hormone-free?

Yes, Estrovera® is a hormone-free plant extract from the root of Rheum rhaponticum (Siberian rhubarb). This special extract, called ERr 731® contains concentrated plant compounds, which act on specific oestrogen receptors throughout the body which helps to relieve menopausal symptoms.​  It is found safe in both animal studies and clinical trials.​3-5 

References
[3] Heger M, Ventskovskiy BM, Borzenko I, Kneis KC, Rettenberger R, Kaszkin-Bettag M, et al. Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints. Menopause. 2006;13(5):744-759. doi:10.1097/01.gme.0000240632.08182.e4

​[4] Wilson M, Konda V, Heidt K, Rathinasabapathy T, Desai A, Komarnytsky S. Rheum rhaponticum Root Extract Improves Vasomotor Menopausal Symptoms and Estrogen-Regulated Targets in Ovariectomized Rat Model. Int J Mol Sci. 2021;22(3):1032. doi:10.3390/ijms22031032

​[5] Dubey VP, Sureja VP, Kheni DB. Efficacy evaluation of standardized Rheum rhaponticum root extract (ERr 731®) on symptoms of menopause: A systematic review and meta-analysis study. J Biomed Res. 2024;38(3):278-286. doi:10.7555/jbr.37.20230219

How does Estrovera® work in the body?

ERr 731™ gently mimics the effects of oestrogen on a specific receptor found throughout the body, called oestrogen receptor beta. This helps to balance the effects of fluctuating oestrogen levels during perimenopause without altering the body's natural hormone levels.3-6

References
[3] Heger M, Ventskovskiy BM, Borzenko I, Kneis KC, Rettenberger R, Kaszkin-Bettag M, et al. Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints. Menopause. 2006;13(5):744-759. doi:10.1097/01.gme.0000240632.08182.e4

​[4] Wilson M, Konda V, Heidt K, Rathinasabapathy T, Desai A, Komarnytsky S. Rheum rhaponticum Root Extract Improves Vasomotor Menopausal Symptoms and Estrogen-Regulated Targets in Ovariectomized Rat Model. Int J Mol Sci. 2021;22(3):1032. doi:10.3390/ijms22031032

​[5] Dubey VP, Sureja VP, Kheni DB. Efficacy evaluation of standardized Rheum rhaponticum root extract (ERr 731®) on symptoms of menopause: A systematic review and meta-analysis study. J Biomed Res. 2024;38(3):278-286. doi:10.7555/jbr.37.20230219

[6] Kaszkin-Bettag M. Beck S, Richardson A, Heger PW, Beer AM. Efficacy of the special extract ERr 731 from rhapontic rhubarb for menopausal complaints: a 6-month open observational study. Altern Ther Health Med. 2008 Nov-Dec;14(6):32-38. PMID: 190439363

How does Estrovera assist with supporting mood symptoms, like irritability?

Low oestrogen levels can increase the activity of enzymes that accelerate the breakdown of feel-good brain chemicals, which can lead to mood changes. By gently stimulating oestrogen receptors, ERr 731™ limits the activity of these enzymes, which can support mood symptoms.7

References
[7] Wei B, Yang ZD, Shi DF, Yao XJ, Wang MG. Inhibition of monoamine oxidase by stilbenes from Rheum palmatum. Iran J Pharm Res. 2016 Fall;15(4):885-892. PMID: 28243286

What happens if I stop taking Estrovera®?

Stopping Estrovera® may result in symptoms returning although women may safely resume taking. However, symptoms may not reappear if a woman has completed her menopausal transition.

What if Estrovera® does not relieve my menopausal symptoms?

Whilst Estrovera® is shown to help most women, around 10% report no improvement. This may be due to other existing health concerns, or the effects of diet, exercise, lifestyle or stress overriding the soothing benefits of Estrovera®. For more personalised insights, please see your healthcare professional to assess if Estrovera® is right for you.

Can I take Estrovera® if I am on the oral contraceptive pill (OCP), hormone replacement therapy (HRT) or menopausal hormone therapy (MHT)?

To ensure Estrovera® is right for you, please discuss with your healthcare professional and/or dispensing pharmacist who can advise on any possible interactions with your medications. 

Overall rating: 4.857143 / 5 from 91 reviews.

AI Generated Review Summary

Estrovera 30 Tablets by Metagenics offers relief from up to 8 common menopause symptoms, including hot flushes, irritability, fatigue, disturbed sleep, vaginal dryness, libido support, and muscle aches. Formulated with a clinically proven extract, ERr 731®, it helps women manage perimenopause and menopause symptoms effectively.

Summary topics

  • Hot Flushes Relief: 16%
  • Hot Flashes Reduction: 24%

Review topics: [results, improvement, quality, work, relief, symptoms, body, difference, energy, flushes, flashes, sleep, night sweats, mood, tablets, nights, supplement].

Review highlights

  • "I’ve been using Estrovera just for 3 weeks and significantly reduced my hot flashes!" — Yuliya A.
  • "Will continue to take and see the improved results as my body adjusts with longer consumption." — Jennifer T.
  • "Finally found a product that works" — Magda S.

Reviews

It actually works!!!

"Amazing! After taking these for nearly a month now, have gone from countless hot flashes during the day and night sweats with broken sleep, to counting on one hand the amount I have had. It took just over a week to notice significant changes. This product has worked for me."

— Amanda B. (5/5)

4/5 as this is a new supplement for me

"Ive been taking Estrovera for just 30 days but in general feeling much better, more energy, less inflammation. As an added bonus,my skin seems to have an improved look as well. This, in combination with Metarelax daily is working for me."

— Jane (4/5)

Happy with the results so far ☺️

"I have been taking Estrovera for around a month now - I can say I have definitely noticed a difference in my mood, the brain fog is clearing. I don’t feel as tired and am feeling more like myself. Very happy so far, 2 months to go on this bottle looking forward to seeing more results."

— Rebecca G. (5/5)

Relief

"This product does exactly what it says it should. Relief for hot flashes particularly at night, helping with a better night sleep and general stable mood throughout the day."

— REBECCA C. (5/5)

"I am pretty certain these are what is making my hair grow and fast! Two months in so time will tell but happy that it is working so far!"

— Vanessa (4/5)

Waste of money

"Told by my doctor that this product was absolutely a waste of time in regards to my symptoms"

— Kerry D. (1/5)

Amazing product, I was a sceptic

"I purchased the pill bottle as a trial as I have been suffering, hot flushes for over 2mths constantly and mood swings, and my sleep has been horrendous, at the end of 1wk taking this, hot flushes had basically gone 2wks no hot flushes and noticing my moods are stabilising, sleep is starting to be more peaceful, I'm so happy and will continue to take Estrovera 😁"

— Jaime (5/5)

Works surprisingly well!

"I initially purchased this to confirm whether I had started perimenopause as symptoms can overlap with other conditions. Within two days of starting Estrovera, both my husband and I noticed that I was back to the “old me” without mood swings and always feeling “on the edge. ” Sleep has also definitely improved and no more night sweats. My endocrinologist was also happy that it’s working well and I will keep taking until symptoms settle down into the new normal."

— Vivian (5/5)

Great Product

"This has eased my menopause symptoms, no night sweats , no hot flushes. I call it my daily happy pill."

— Julie M. (5/5)

Great product

"Exactly what I needed and delivered in a shorter than expected time."

— Jeanette (5/5)

Q&A

**Money Back Offer T&Cs apply. Subject to claim dates and promotional period.

*Hasper et al. Long-term efficacy and safety of the special extract ERr 731® Rheum rhaponticum. 2009. 
^Survey conducted online by Metagenics September 2020 with 75 women currently taking Estrovera.

 1. Wober J, Möller F, Richter T, Unger C, Weigt C, Jandausch A, et al. Activation of estrogen receptor-beta by a special extract of Rheum rhaponticum (ERr 731), its aglycones and structurally related compounds. J Steroid Biochem Mol Biol. 2007 Nov-Dec;107(3-5):191-201. doi: 10.1016/j.jsbmb.2007.04.00

2. Shah J, Chandanani S, Reddy J, et al. Evaluation of the efficacy and safety of Rheum rhaponticum root extract (ERR 731) for menopausal symptoms in perimenopausal Indian Women: An Interim Analysis. J Midlife Health. 2021;12(2):108-115. doi:10.4103/jmh.jmh_86_21